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RID3678 uveomeningitic syndrome

synonym

Uveomeningeales Syndrom
VKH syndrome
Vogt-Koyanagi-Harada syndrome

definition

A syndrome characterized by bilateral granulomatous uveitis with iritis and secondary glaucoma, premature alopecia, symmetrical vitiligo, poliosis circumscripta (a strand of depigmented hair), hearing disorders, and meningeal signs (neck stiffness and headache). Examination of the cerebrospinal fluid reveals a pattern consistent with meningitis, aseptic. (Adams et al., Principles of Neurology, 6th ed, p748; Surv Ophthalmol 1995 Jan;39(4):265-292) [MeSH]

comment

associated with panuveitis, exudative retinal detachment, optic nerve hyperemia, vitiligo, alopecia, meningismus, dysacusis