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RID4048 gliosarcoma

synonym

Gliosarkom
gliosarcoma (WHO grade IV)

definition

Rare mixed tumors of the brain and rarely the spinal cord which contain malignant neuroectodermal (glial) and mesenchymal components, including spindle-shaped fibrosarcoma cells. These tumors are highly aggressive and present primarily in adults as rapidly expanding mass lesions. They may arise in tissue that has been previously irradiated. (From Br j neurosurg 1995 Apr;9(2):171-8) [MeSH]