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RID4243 bronchioloalveolar carcinoma

synonym

BAC
Bronchioalveolares Karzinom
alveolar cell carcinoma
bronchioalveolar cell carcinoma
bronchiolo-alveolar carcinoma
bronchoalveolar carcinoma
bronchoalveolar cell carcinoma

definition

A carcinoma thought to be derived from epithelium of terminal bronchioles, in which the neoplastic tissue extends along the alveolar walls and grows in small masses within the alveoli. Involvement may be uniformly diffuse and massive, or nodular, or lobular. The neoplastic cells are cuboidal or columnar and form papillary structures. Mucin may be demonstrated in some of the cells and in the material in the alveoli, which also includes denuded cells. Metastases in regional lymph nodes, and in even more distant sites, are known to occur, but are infrequent. (From Stedman, 25th ed) [MeSH]