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RID4418 supratentorial primitve neuroectodermal tumor

synonym

PNET
Supratentorieller primitiver neuroektodermaler Tumor
cerebral ganglioneuroblastoma
cerebral medulloblastoma
cerebral neuroblastoma
supratentorial primitve neuroectodermal tumor (WHO grade IV)

definition

A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., neuroectodermal tumors, primitive, peripheral). This term is also occasionally used as a synonym for medulloblastoma. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059) [MeSH]