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RID49521 atypical small acinar proliferation

synonym

ASAP
atypical small acinar proliferation of uncertain significance

definition

Atypical foci suspicious for, but not diagnostic of, adenocarcinoma. Defined as a focus of small acinar structures formed by atypical epithelial cells, in needle prostate biopsy,that is quantitatively and/or qualitatively insufficient for definitive diagnosis or exclusion of prostate cancer. Strong predicitve factor associated with prostate cancer. Repeat biopsy is indicated.