0004353 Abnormality of pyrimidine metabolism
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0003267 Reduced orotidine 5-prime phosphate decarboxylase activity
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The enzyme orotidine-5-prime-phosphate decarboxylase (EC 4.1.1.23) catalyzes the reaction H(+) + orotidine 5'-phosphate = CO(2) + UMP (uridine monophosphate). The enzyme is thusinvolved in pyrimidine biosynthesis.