0005527 Reduced kininogen activity

synonym Fitzgerald factor deficiency Kininogen deficiency Williams factor deficiency Williams-Fitzgerald-Flaujeac factor deficiency

comment Kininogen is cleaved into the following 6 chains: 1) Kininogen-1 heavy chain; 2) T-kinin; 3) Bradykinin; 4) Lysyl-bradykinin; 5) Kininogen-1 light chain; and 6) Low molecular weight growth-promoting factor.