0003256 Abnormality of the coagulation cascade
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0010989 Abnormality of the intrinsic pathway
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The intrinsic pathway requires coagulation factors VIII, IX, X, XI, and XII, as well as the proteins prekallikrein (PK) and high-molecular-weight kininogen (HK or HMWK), in addition to calcium ions and phospholipids secreted from platelets.
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0001929 Reduced factor XI activity
0001976 Reduced antithrombin III activity
0004841 Reduced factor XII activity
0005527 Reduced kininogen activity
0011858 Reduced factor IX activity
0030976 Abnormal factor VIII activity
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